This is a big negative for two reasons
Third, hyperhomocysteinemia detected both under basal conditions and after a methionine challenge (approximately 50% of patients), which might be partially explained by a saturation of the transsulfuration pathway caused by dietary methionine excess
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For background on the copper tripeptide itself, Wikipedias GHK-Cu overview provides foundational context
No adverse effects, allergic reactions, or irritation have been reported at concentrations up to 3%
Peptides in Perimenopause: A Physician's Cautiously Curious Perspective Written and edited by Sarah Bonza MD, MPH, FAAFP, MSCP, DipABLM, NBC-HWC As a board-certified family physician and Menopause Society Certified Practitioner, I've built my practice on evidence-based medicine