Last but not least, GSH participates in non-enzymatic conjugation with some chemicals, for instance, it is hypothesized that glutathione reacts with n-acetyl-p-benzoquinone imine (NAPQI) -the cytochrome P450 reactive metabolite formed by toxic overdose of acetaminophen- to detoxify it.
* Correspondence: Gen Ohtsuki, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
[Abstract] Appl Microbiol Biotechnol
Sie setzen die Zelle oxidativem Stress aus und mssen schnell neutralisiert werden, bevor es zu Schden an den Zellstrukturen (Mitochondrien, Zellkern/DNA, Zellmembran) kommt
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