We observed the dissociation of p53 TAD (13-61) from FOXO4 FHD upon the addition of p53 TAD PEP, resulting in a chemical shift of the 15 N-p53 TAD-FOXO4 FHD complex towards the unbound state of p53 TAD (Figure
The fascinating link between the two lies in their shared amino acid profile
Janvier, S., Cheyns, K., Canfyn, M., Goscinny, S., De Spiegeleer, B., Vanhee, C., & Deconinck, E
In both mice and humans, two homologs have been identified: CHAC1 and CHAC2
Hermann Aesthetics
This movement enables an increased pool of GSSG in the cell for potential use by specific glutathione enzymes like GST, emphasizing the importance of glutathione-associated enzymes as key molecules in the resistant response