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Inhibition of integrin 3 or Src can improve the anti-cancer activity of cixutumumab in cixutumumab-resistant cell lines and patient-derived tumors [172]
doi: 10.1007/s11064-021-03320-2 216 DuanLZhangYYangYSuSZhouLLoPCet al
Second, determining the ideal timing and priority to intensify therapy is also urgently required, since present evidence are not enough to cover this evidence gap
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