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Translation to human clinical application has been limited for both compounds

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PMID: 39220257 Solvent & Solubility In Vitro : DMSO : 50 mg/mL ( 131.59 mM

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There is an increased risk of suicidal ideation and behavior in patients receiving AEDs to treat epilepsy, psychiatric disorders, or other conditions (e.g., migraine, neuropathic pain)

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