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People with Lebers hereditary optic neuropathy, a rare inherited optic nerve disorder, may be at risk of severe optic nerve damage with cyanocobalamin

Some common signs of B12 deficiency include: Low energy or fatigue (even after a good nights sleep) Brain fog or memory lapses Mood swings, anxiety, or irritability Numbness or tingling in hands and feet Poor immune function Sound familiar

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This distinction helps explain why it progressed into formal obesity trials, whereas the raw fragment itself did not

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