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These supplements play a critical role in maintaining energy levels, preventing muscle breakdown, and mitigating the effects of reduced vitamin intake when consuming fewer calories during weight loss

It is not a casual medication

Drug Metab Dispos 33 , 649656, doi: dmd.104.002964 [pii]10.1124/dmd.104.002964 (2005)

Adequate fluid intake helps fiber do its job by softening the stool and preventing constipation, which is especially important when your appetite is suppressed, says Salhab

Typically mild to moderate, peaking 1-3 days after dose increases and gradually subsiding over 1-2 weeks

The GLP-1 and GIP components help counterbalance this effect, but the titration schedule accounts for it by allowing the body to find equilibrium at each dose level before escalating