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Such alterations have been noted in individuals with type 2 diabetes, obesity, and metabolic syndrome, though the precise mechanisms remain an active area of research

Can Res 55:47714775 Mulcahy RT, Gipp JJ (1995) Identification of a putative antioxidant response element in the 5'-flanking region of the human gamma-glutamylcysteine synthetase heavy subunit gene

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