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The researchers concluded that short-term administration of sermorelin to healthy older men reverses age-related decreases in GH and may improve body composition with prolonged treatment

They work by regulating blood sugar, reducing appetite, and improving metabolic function

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The available human pharmacokinetic study involved only 18 healthy adults receiving a single high dose

(Frontiers in Pharmacology, 2022) reports a half-life under 30 minutes after IM or IV administration in rodent and dog models, which is why split-dose schedules appear in the literature