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Managing the Transition: Medical Supervision and Lifestyle Strategies If discontinuation is unavoidable, medical supervision during the transition reduces symptom severity and supports metabolic adjustment

Syn-Ake relaxes expression lines

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injections of 100 nmol kg 1 PYY analogue ( n = 7 mice and n = 6 cages), 100 nmol kg 1 PYYMK-801 ( n = 7 mice and n = 4 cages), 100 nmol kg 1 GLP-1MK-801 ( n = 7 mice and n = 5 cages) or vehicle (isotonic saline, n = 7 mice and n = 4 cages) for 6 days

Selank is a synthetic polypeptide

Supplementary Section 3)