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The bottom line: dose matters less than dose integrity
That literature has explored its role across tendon, muscle, gut and vascular models, and its frequently cited in the wider tissue-repair field
Read together with the failed fosgonimeton trial, the takeaway is that the human-relevant evidence base for this class is both thin and, where it touched humans, negative
Translational Vision Science & Technology, 10 (8), 4
ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury
However, evidence remains insufficient
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