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Bielohuby, et al (2012)

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During semaglutide therapy, patients with a history of diabetic retinopathy should be closely monitored

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This is because glutathione deficiency contributes to oxidative stress, which plays a key role in these and other disease pathogenesis such as seizures, Alzheimers disease, liver disease, sickle cell anemia, cancer, heart attack, stroke, and diabetes