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Thus, understanding how pharmacy and medical benefit design affects GLP-1 coverage is critical

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Weight-loss drugs are saving users households more than 400 a year on grocery bills, according to a survey, which found use of GLP-1s has nearly tripled in the past two years to 1.9 million adults

Consistent with perturbed glutathione metabolism, CLP mice exhibited significant downregulation of the Nrf2/HO-1 antioxidant axis: reduced Nrf2, a master transcriptional regulator of antioxidant genes, and its target HO-1 were reduced, indicating impaired upstream antioxidant regulation