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the clinical significance in humans remains under investigation and is not yet established for retatrutide specifically [24] [25] Other class-associated cautions: Based on the broader GLP-1/GIP receptor agonist class, potential effects on gallbladder function and delayed gastric emptying are relevant considerations, though evidence specific to retatrutide is still emerging It is important to note that this evidence derives from early-phase trials conducted under controlled conditions with medical supervision
J Biol Chem 264(17):98149819 Conflict of interest The author declares that he has no conflict of interest
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Or to frame it differently, researchers using oral acetate BPC-157 may have been receiving only a fraction of the intended dose, which could explain the inconsistent results that some users reported with oral BPC-157 protocols
