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& Gorrell, M
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Notably, LONP1s DNA-binding capacity is regulated by ATP concentration and protein substrate levels: elevated ATP concentrations reduce its DNA-binding affinity, whereas increased protein substrate levels enhance its binding strength by approximately 3.5-fold [50]
doi:10.2337/dc19-2046 Giacco F, Brownlee M
De Blasio MJ, Huynh K, Qin C, Rosli S, Kiriazis H, Ayer A, Cemerlang N, Stocker R, Du XJ, McMullen JR, Ritchie RH (2015) Therapeutic targeting of oxidative stress with coenzyme Q10 counteracts exaggerated diabetic cardiomyopathy in a mouse model of diabetes with diminished PI3K(p110alpha) signaling
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