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Regulators may consider the complete presentation, claims, intended purpose and pharmacological context
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Chronic or Persistent Diarrhea Diarrhea that lasts several weeks or longer and does not resolve which can also lead to malnutrition, dehydration and a hospital stay
When GLP-1 binds to these receptors, it directly influences their function: Macrophages: GLP-1s can shift macrophages from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype, reducing inflammation in tissues like fat
In animal studies, GLP-1 drugs were found to cause thyroid C-cell tumors
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