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41,45,52 Paradoxically, while Hb increases in the cerebrospinal fluid of mild cognitive impairment patients, 53 acute H 2 O 2 exposure in astrocytes increases Hb mRNA and opens its promoter regions (Supplementary Fig

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This interview has been edited and condensed for clarity .

AM resulted in remarkable mitochondrial shrinkage, enhanced Fe 2+ and ROS levels, and significantly decreased mRNA and protein expression of SLC7A11 and GPX4 in breast cancer cells, indicating that AM suppressed cell growth and invasion via ferroptosis (Zhang J