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doi:10.1016/j.mimet.2005.01.010

The injection should be administered slowly and steadily, and the needle should remain in place for several seconds after injection to ensure complete delivery of the dose

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Published clinical pharmacokinetic studies comparing IM injection sites show that peak plasma concentration (Cmax) values can vary by 1525% between different IM sites for the same compound and dose, making site consistency critical for reproducible subcutaneous vs intramuscular peptide injection research outcomes

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