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The problem with prolonged caloric deficit is that metabolic adaptation your body downregulates energy expenditure over time to resist the deficit

10.3390/biom15040500 104 MaugeriN.RadhakrishnanJ.KnightJ

The causes of conflicting results in trials examining vitamin D status have been suggested to be differences in cut-off for vitamin D sufficiency, differences in the groups in which the trials were conducted, and differences in the measurement tools used.In addition to the fact that vitamin D deficiency causes neuropsychiatric disorders or that dietary intake/supplementation has a role in the treatment of neuropsychiatric disorders alone, it has been shown to have an adjuvant role in patients treated with SSRIs

Use should be discontinued upon observing any adverse reaction

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These considerations highlight the importance of evaluating supplements within a clinically integrated framework rather than as isolated adjuncts