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By inhibiting P-gp, these agents enhance cellular drug retention but may inadvertently increase systemic drug concentrations, posing toxicity risks for narrow-therapeutic-index medications (e.g., chemotherapeutics, cardiovascular drugs) (32, 8890)
What Are GLP-1 Medications and How Do They Work
The IV route remains the most efficient way to deliver clinically meaningful doses
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doi: Nauck, M.A., Quast, D.R., Jakob Wefers and Meier, J.J
Regulators in Delaware and New Mexico approved 2025 individual-market increases of 25% to 35%, with New Mexico citing higher-than-expected claims and rising medical costs, and Delaware pointing to federal budget activity and the expiration of enhanced premium tax credits
