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More about this will be addressed in section 2.2

While translational gaps persist, particularly in dosing, timing, and patient stratification, emerging strategies including mitochondria-targeted antioxidants, nanotherapeutics, and biomarker-guided interventions hold promise for restoring redox homeostasis and improving clinical outcomes

This polarization enhances the tumor-supportive environment, as M2 macrophages secrete anti-inflammatory cytokines that facilitate cancer cell proliferation and invasion

The level of endothelial dysfunction was strongly associated with the amount of metabolic components of the ATP-III criterion present in each participant

PMID: 39191757 Nat Commun 2026 Mar 13;17(1):3879