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For patients with Long COVID or ME/CFS, practitioners often recommend starting with a smaller dose (e.g., 1/4 or 1/2 scoop) to assess tolerance, as rapid detoxification can sometimes cause a temporary exacerbation of symptoms (a Herxheimer reaction) as toxins are mobilized

Neurotoxicology 36, 6371 (2013)

Cammarota et al., 2015

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When taken as a liquid, glutathione is absorbed through mucous membranes which quickly delivers a high-dosage of glutathione directly to the bloodstream

doi: 10.1530/EJE-12-0501 29 WattTHegedsLKrogh RasmussenAGroenvoldMBonnemaSBjornerJet al