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Amplification of EGFR signaling has been observed in 35-45% of GBM with wild-type IDH (38), most commonly occurring via an exon deletion that leads to a constitutively active receptor (39)

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However, the lack of a thorough understanding of the role of PTMs in shaping the behavior of p53 mutants limits the development of more precise therapeutic strategies

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Peng, M., Cai, Y., Fang, X

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We searched two databases for DKD-related research reports to identify potential targets

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