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"What people are shooting up with out there I would give to mice." The influencer crowd has sort of created this perception that these are miracle drugs." @mkaeberlein New feature @Nature nature.com/articles/d4158 The most popular unapproved peptide is probably retatrutide, which both works extremely well and has a lot of science behind it

PubMed PMID: 35013352

Unlike conventional vasodilators that lower blood pressure regardless of baseline, penta deca peptide arginate appears to normalize blood pressure from either direction

Central nervous system applications are an active growth area, with documented effects on dopamine and serotonin pathway markers, traumatic brain injury models, and spinal cord research preparations

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And absent more rigorous studies, the team warned, it will remain difficult to convince the broader medical community that this so-called wonderful compound meets the criteria of a legitimate therapeutic agent. But it turns out, one group had begun to give it a go anyway