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6 Limitation and future research priorities Despite the promising potential of ferroptosis-targeting therapies, several limitations currently hinder their translation into clinical practice

In order to lower population-level reproductive risk, policy measures including tighter regulation of endocrine-disrupting chemicals, microplastic management, better air quality standards, and monitoring heavy metal pollution in water and food systems are important

Breastfeeding is not recommended because serious side effects could occur for the baby

TXN contains two redox-active cysteine residues and can be oxidized when reducing the disulfides within the oxidized proteins