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On the other hand, DPP-4 inhibitors augment the half-life of endogenous GLP-1 by impeding its degradation

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Yes Stop the other GLP-1 entirely before starting semaglutide

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and (2) peptides without FDA approval

Testing may include: Dilated eye exam Optic nerve evaluation Retinal imaging OCT scan of the optic nerve and macula Visual field testing Blood pressure and medical history review Discussion of diabetes, sleep apnea, cholesterol, and cardiovascular risk factors Your eye doctor may also coordinate care with your primary care doctor, endocrinologist, or prescribing provider if there are concerns