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This dual benefit is unique among current GLP-3 class peptides
According to the MHRA SmPC, semaglutide does not reduce the efficacy of hormonal contraceptives, though severe vomiting or diarrhoea may potentially affect the absorption of oral contraceptive pills, requiring temporary additional contraceptive measures
One study using 24-hour ambulatory blood pressure monitoring found significant reductions in systolic blood pressure compared to placebo
In practice, it's most useful as an adjunct to established hair-loss treatments rather than a standalone therapy
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The same dopamine effect is why bupropion is also approved for smoking cessation (as Zyban) and is used off-label for ADHD-like symptoms
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