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This triple-action mechanism distinguishes retatrutide from existing approved therapies such as semaglutide (a GLP-1 receptor agonist) or tirzepatide (a dual GIP/GLP-1 receptor agonist), though no head-to-head clinical outcome trials comparing these agents have yet been published
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However, tirzepatide can also come with temporary side effectssuch as nausea, fatigue, or appetite changesthat may affect emotional well-being in the short term
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The study, published Dec
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