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B12 Injections are contraindicated if you have any of the following conditions: Chronic liver disease, including hepatitis, and/or kidney dysfunction Individuals with sensitivity to cobalt and/or cobalamin and those with Lebers disease, a hereditary optic nerve atrophic condition, as it can lead to blindness

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Apply after cleansing and before heavier moisturizers or SPF

Funding This work was supported by the Henan Provincial Breast Cancer Precision Prevention and Control Engineering Research Center (ZC20220050), the Henan Provincial Peoples Hospital23456 Talent Engineering Project (ZC23456026) and the study on the Effect and Mechanism of Macrophage-Derived Exosomes Loaded with Doxorubicin for Targeted Therapy of Triple-Negative Breast Cancer (ZC20220114)