This higher occurrence stems from several age-related factors, including reduced gastric acid production (hypochlorhydria), pernicious anaemia (autoimmune destruction of intrinsic factor), and sometimes decreased dietary intake
References Raun, K., Hansen, B.S., Johansen, N.L., Thgersen, H., Madsen, K., Ankersen, M., & Andersen, P.H
however, two additional legumes (broad bean and lupine) appear to lack this glutathione analog in all assayed tissue types (Matamoros et al., For biosynthesis of glutathione and homoglutathione share a common first reaction, i.e., the synthesis of -glutamylcysteine, but the chemical diversity results from altered specificity for the nucleophilic amino acid in the second reaction of the pathway
They target different receptors involved in Growth Hormone release, creating complementary signaling pathways
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Clin Physiol 1984;4(4):363-365