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Studies have indicated that Zn-induced overexpression of MT in pancreatic -cells can confer notable protection against streptozotocin-induced diabetes in both rats and mice [125]
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Although ligand-receptor pathways are often thought of as linear paths from engagement to transcription/translation, many studies show that enhanced oxidative potential can augment or suppress signaling pathways, including those related to MUC5AC, while more recently, oxidatively driven epigenetic effects on gene transcription have also been reported (2932)
10.1186/s13098-024-01280-5 43
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