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It has been shown that PDT has some efficacy in treating PVL, particularly in large, thick, or highly keratinized lesions, although the evidence remains limited

243,244,245 The binding of chemoattractants to GPCR activates the pertussis toxin-sensitive heterotrimeric G proteins of the G i/o family, signaling to downstream pathways

Reconstitution: 3.0 mL per 5 mg vial (~1.67 mg/mL) for practical volume measurements

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Toxication occurs when high concentrations of the drug are ingested

Not yet as of 2026-05