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387 Urate oxidase catalyzes the breakdown of uric acid into 5-hydroxyisourate, which subsequently undergoes spontaneous degradation to allantoin without enzymatic assistance
Furthermore, Bao et al
The N-terminal domain I is connected to the C-terminal domain II by a linker loop region consisting of around 10 amino acids [42, 62, 76]
It reflects a broader shift in how HHS under Secretary Kennedy is approaching the intersection of patient access, clinical innovation, and regulatory oversight
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