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Description

NMN treatment improved mitochondrial stability We used dissociated motor cortex cultures isolated from prpTDP-43 A315T -UeGFP mice to investigate the basis of NMN-mediated improvement in CSMN health

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Suicidality: under active investigation Regulatory bodies, including the European Medicines Agency, have been reviewing a potential association between GLP-1 drugs and suicidal ideation

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We think this could lead to new interventions, such as reducing the glutathione overload through synthesis inhibitors or compounds that can dissipate it. The findings also have implications for potential therapies for lung cancers related to mutations in the KEAP1 gene

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Statistical significance was determined using two-tailed Students t test through GraphPad Prism5 software unless otherwise mentioned

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