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The weight loss during the first 5-10 pounds is water weight because the drug makes patients urinate more often

Alternatively, switching to a different GLP-1 medication may be considered if side effects are intolerable, as individual responses vary between agents

energy kJ (kcal)

Similarly, major cardiovascular outcome trialsincluding LEADER (liraglutide), SUSTAIN-6 (semaglutide), EXSCEL (exenatide), and REWIND (dulaglutide)reported pancreatic cancer incidence rates that were comparable between treatment and placebo groups

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