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Without pharmacokinetic data on sublingual tirzepatide absorption patterns, there is no scientific basis to recommend one dosing frequency over another

The workaround many prescribers use: if a non-diabetic patient also has a comorbidity that a GLP-1 drug treats (cardiovascular disease for Wegovy, sleep apnea for Zepbound), the prescriber can request coverage under that indication

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[6] Vujacic, M., Marinkovic, M., Radosavljevic, J., et al

April 2026 Category 2 Update On April 15, 2026, the FDA confirmed removal of injectable GHK-Cu from Category 2 because the original nominations were withdrawn

This is why it is typically viewed as a safe medication for donors, provided the donor feels healthy