Increases in the expression of various molecules that have been noted in reactive astrocytes across multiple contexts include GFAP, vimentin, nestin (probably labelling proliferating astrocytes), synemin plectin, -crystallin B chain, monoaminoxodase-B (MAO-B), heat shock factor binding protein 1, complement C3, lipocalin 2, C-X-C motif chemokine ligand 10, SerpinA3N, LCN2 and others, 20,95,96,97,98,99,100,101,102,103 but it important to note that no single molecular marker (including GFAP) is an absolute, required and sufficient, indicator of astrocyte reactivity, and no molecular markers have yet been identified that reliably distinguish amongst different reactive astrocyte phenotypes
Aging is not associated with proteasome impairment in UPS reporter mice
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Rather than targeting an isolated cellular mechanism, this advanced 30,000mcg matrix integrates three highly active synthetic peptide architectures: a stable gastric pentadecapeptide, a functional thymosin beta-4 fragment, and a potent copper-binding signaling complex
The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum
doi: 10.3233/jad-160152 35 LevineKSLeonardHLBlauwendraatCIwakiHJohnsonNBandres-CigaSet al
