Naimi RM, Hvistendahl M, Nerup N, Ambrus R, Achiam MP, Svendsen LB, et al
Pharmacological considerations currently focus on managing associated metabolic and cardiovascular conditions rather than directly treating the liver
Anti-Inflammatory Effects: TB-500 may blunt inflammation at a broader level, potentially easing whole-body soreness and joint stiffness useful for women in high-intensity sports or during perimenopause, when inflammation may already be higher
Kidney issues can require dialysis or result in permanent damage
1,2 Current therapies for HS, including adalimumab, secukinumab, bimekizumab, oral and topical antibiotics, and anti-inflammatory agents, fail to address one of the root causes, the metabolic and inflammatory burden, which could be an important driver of the disease
BPC157 also appears in studies to play a key role in protecting the gastrointestinal lining, and gut-wall integrity, with research into gutbrain interactions, making it of particular interest in clinical trials related to managing leaky gut, Crohns disease, and NSAID-induced ulcers