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Preclinical cartilage evidence Kwon and Park 2015 in Annals of Clinical and Laboratory Science reported that intra-articular AOD-9604 plus hyaluronic acid in a rabbit knee osteoarthritis model improved cartilage histology and reduced lameness compared with hyaluronic acid alone

ONE SIZE FITS ALL cannot ever be possible in this situation

Higher doses beyond 0.5 mg havent shown significantly better results in clinical trials

Wuppermann 31 studied fibrinolysis in subjects injected with POL and found a slight, statistically insignificant hyperfibrinolysis in blood drawn from the antecubital vein

For example, a patient with severe flu and poor intake might get weekly shots for a month and then stop once theyre eating well