Right now, there is no clear answer on whether tirzepatide is safe during breastfeeding
Lancet 376 (9736), 190201
When to Seek Medical Advice About Missed Periods Whilst occasional menstrual irregularities can be benign, certain circumstances warrant prompt medical evaluation
A reader is best served by holding two things at once: the mechanism is genuinely interesting, and the human evidence does not yet exist
While there's no direct proof that these GLP-1 drugs are driving the drops we're now seeing in obesity rates, given their increasing use and how effective we know they are, it seems likely
Further support was provided by the Uehara Memorial Foundation, Kanae Foundation for the Promotion of Medical Science, Mochida Memorial Foundation for Medical and Pharmaceutical Research and the Human Frontier Science Program, plus the Medical Scientist Training Program and Pharmacology Training Grant at UC San Diego (T32GM007752)