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In the UK, orlistat can be considered for people with a BMI 28 kg/m with risk factors or 30 kg/m

In April 2020, the drug was approved for those aged 12 and over, too

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Strong clinical trial results, widespread physician adoption, and high patient preference for oral administration enhance its market leadership

Rapid weight loss from any cause can reduce bone density

GLP-1 enhances glucose absorption and utilisation in muscle and adipose tissue by facilitating the translocation of GLUT4 to the cell membrane (Chang et al