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Alpha synuclein has also been shown to directly generate hydrogen peroxide when it aggregates and, in the presence of iron, produce toxic hydroxyl radicals

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their effect on blood sugar and cardiometabolic risk matters too

That matters because compounded drugs (whether under FDCA 503A or 503B) may be exempt from certain approval requirements, but they are not FDAapproved and those exemptions are conditioned on meeting specific statutory requirements