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206 A placebo-controlled crossover trial in adults over 65 years old compared the immediate short-term effects of single doses (167 mg, 333 mg, 666 mg, or 1,332 mg) of a standardized sage extract on cognitive performance at 1, 2.5, 4, and 6 hours post-dose
Singh S, Keller PR, Busija L, et al
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That said, oral supplementation is not without value when sustained over longer periods
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