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Esler WP, Rudolph J, Claus TH, et al

The total radioactivity concentrations in the kidney, liver, stomach wall, thymus, spleen, intestine, lung, skin, and body fat were reduced by approximately 50% compared with the peak concentration in the same tissue (1 h after administration)

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Minimum requirements vary by state: Florida requires at least every 3 months, Virginia every 30 days, New Jersey mandates specific intervals based on medication type