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A negligible fraction of cells were propidium iodide + alone, indicating that X(PC) does not merely initiate unprogrammed necrotic cell death in SUP-B15 cells but rather directly activates a pyroptotic lytic death through caspase activation
Nat Cell Biol 11(11):13051314
Inhibition of COX-1 activity by non-selective NSAIDs (such as aspirin or ibuprofen) results in degradation of the protective mucus layer (Vonkeman 2010)
Doi: 10.1016/j.biopha.2020.110984
Bacteria produce enzymes that break peptide bonds
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