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The shoulder Experienced doctors commonly administer B12 injections into the upper arm area by inserting the injection into the deltoid (shoulder) muscle

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Several factors can affect results: Age and sex Pregnancy Fasting status Hydration Recent exercise Acute illness Supplements and other medications Anemia Kidney function Weight and body-composition changes Laboratory methodology An abnormal result does not always indicate disease, and a normal result does not always exclude a clinically important problem

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The presence of previous neurological damage from B12 deficiency may necessitate more frequent injections to prevent symptom recurrence, even after initial improvement

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