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Tirzepatide is a dual agonist meaning it targets both GLP-1 and GIP receptors

Stomach problems, sometimes severe, have been reported in people who use Ozempic (semaglutide)

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Incretin-based multi-agonists, such as tirzepatide and retatrutide, target two or more receptors among GLP-1, GIP, and GCGR to enhance insulin secretion, improve fat metabolism, and increase energy expenditureultimately achieving greater weight loss and metabolic improvement