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The 200 mcg figure that appears across forums and vendor sites is not from a clinical guideline
Tirzepatide pivotal trials demonstrated that nausea and abdominal discomfort affected 2540% of participants during early treatment phases, but fewer than 5% discontinued therapy due to GI side effects
Together, these effects may lead to weight loss and reductions in body fat
Semaglutide users commonly report nausea (2030%) and constipation as digestion slows, while tirzepatides GIP activity may trigger more frequent diarrhea (1525%)
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