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Int J Mol Sci, 2020
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[6] Research [edit] BPC-157 was discovered by Predrag Sikiric, a researcher in Zagreb, Croatia who published it in 1993 in Journal of Physiology, Paris
F2-isoprostanes (F2-IsoPs) are potent vasoconstrictors (35)These compounds are similar to prostaglandins, and they are produced during non-enzymatic ROS peroxidation of polyunsaturated fatty acids (PUFAs), mainly arachidonic acid
Through precise chemical modifications and functional group introduction, we ensure acid cleavable linkers remain stable in blood circulation yet efficiently cleave in acidic environments, achieving effective drug release