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The occurrence of ferroptosis in mature erythrocytes has not been confirmed and it seems quite challenging, since ferroptosis studies suffer from the lack of well-established markers and evaluation of this cell death requires a complex approach with identification of typical cellular and subcellular morphological alterations, genetic hallmarks, biochemical changes, expression of certain ferroptosis-related proteins, etc
This remains true for endemic cases of norovirus infection, which are primarily facilitated by the low infectious dose of between 18 and 1000 virus particles
[10] In living organisms, the process is normally catalyzed by enzymes known as peptidases or proteases, although there are reports of peptide bond hydrolysis caused by conformational strain as the peptide/protein folds into the native structure
Scientific Reports 2021 Wintermute GK et al Clinical Oral Investigations 2024 Salgado Peralvo A et al
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